Archived Publications 2004-2006

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2006

Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells.
David Cobrinik, Richard O Francis, David H Abramson, and Thomas C Lee. Dec 2006, Mol Cancer. 2006; 5: 72. doi: 10.1186/1476-4598-5-72

Cutting Edge: Role of TANK-Binding Kinase 1 and Inducible I_B Kinase in IFN Responses against Viruses in Innate Immune Cells
Kosuke Matsui, Yutaro Kumagai, Hiroki Kato, Shintaro Sato, Tatsukata Kawagoe, Satoshi Uematsu, Osamu Takeuchi, and Shizuo Akira.
The Journal of Immunology, November 2006, 177: 5785-5789

Microarray analysis of thyroid nodule fine-needle aspirates accurately classifies benign and malignant lesions
Carrie C. Lubitz, Stacy K. Ugras, J. Jacob Kazam, Biaxin Zhu, Theresa Scognamiglio, Yao-Tseng Chen and Thomas J. Fahey, III. November 2006, Journal of Molecular Diagnostics. 2006; 8: 490-498

Functional genomic methodologies
Stephen D. Ginsberg and Károly Mirnics. 2006, Progress in Brain Research, Vol. 158; 15-40. PMID: 17027690

TAT-BH4 and TAT-Bcl-xL Peptides Protect against Sepsis-Induced Lymphocyte Apoptosis In Vivo1
Richard S. Hotchkiss, Kevin W. McConne, Kristin Bullok, Christopher G. Davis, Katherine C. Chang, Steven J. Schwulst, Jeffrey C. Dunne, Gunnar P. H. Dietz, Mathias Bähr, Jonathan E. McDunn, Irene E. Karl, Tracey H. Wagner, J. Perren Cobb, Craig M. Coopersmith and David Piwnica-Worms. 2006, The Journal of Immunology, 2006, 176: 5471-54770

Automated Solutions for Total RNA Isolation from Diverse Sample Types.
Paula Selley, Jimmy Bruner, Fiona Kelly, Frank Maurio, Michelle Waters and Jay Strum. Oct 2006, Journal of the Association for Laboratory Automation, Volume 11, Issue 5, 309-313

Derivation of human embryonic stem cells from developing and arrested embryos
Xin Zhang, Petra Stojkovic , Stefan Przyborski, Michael Cooke, Lyle Armstrong, Majlinda Lako, Miodrag Stojkovic.
Stem Cells Express, published online September 2006; doi:10.1634/stemcells.2006-0377

Development of heart valves requires Gata4 expression in endothelial-derived cells
José Rivera-Feliciano, Kyu-Ho Lee, Sek Won Kong, Satish Rajagopal, Qing Ma, Zhangli Springer, Seigo Izumo, Clifford J. Tabin and William T. Pu.
Development 133, 3607-3618, September 2006, doi:10.1242/dev.02519

Replacing cRNA targets with cDNA reduces microarray cross-hybridization
Aron C Eklund, Leah R Turner, Pengchin Chen, Roderick V Jensen, Gianfranco deFeo, Anne R Kopf-Sill& Zoltan Szallasi. September 2006, Nature Biotechnology 24: 1071 - 1073
doi:10.1038/nbt0906-1071

Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators
M. A. Keller, S. Addya, R. Vadigepalli, B. Banini, K. Delgrosso, H. Huang, and S. Surrey.
Physiol Genomics 28: 114-128, August 2006; doi:10.1152/physiolgenomics.00055.2006.

Gene Expression Profiles Identify Epithelial-to-Mesenchymal Transition and Activation of Nuclear Factor-K B Signaling as Characteristics of a High-risk Head and Neck Squamous Cell Carcinoma
Christine H. Chung, Joel S. Parker, Kim Ely, Jesse Carter, Yajun Yi, Barbara A. Murphy, K. Kian Ang, Adel K. El-Naggar, Adam M. Zanation, Anthony J. Cmelak, Shawn Levy, Robbert J. Slebos and Wendell G. Yarbrough. August 2006, Cancer Research 66, 8210-8218

Reversal of Hox1 Gene Subfunctionalization in the Mouse
Petr Tvrdik and Mario R. Capecchi. August 2006, Developmental Cell, Vol 11, 239-250

Nephritogenic Anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells
Xiaoping Qing, Jiri Zavadil, Michelle B. Crosby, Mark P. Hogarth, Bevra H. Hahn, Chandra Mohan, Gary S. Gilkeson, Erwin P. Bottinger, Chaim Putterman.
Arthritis & Rheumatism, July 2006, Volume 54 Issue 7, Pages 2198 - 2210 27

Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue
Liton PB, Luna C, Challa P, Epstein DL, Gonzalez P. July 2006, Molecular Vision, 12:774-90

Preliminary Comparison of Quality, Quantity, and Microarray Performance of RNA Extracted from Formalin-Fixed Paraffin-Embedded and Unfixed Frozen Tissue Samples
Marshall S. Scicchitano , Deidre A. Dalmas, Melissa A. Bertiaux, Shawn M. Anderson, Leah R. Turner, Roberta A. Thomas, Rossana Mirable, Rogely W. Boyce. First published JHC exPRESS, July 2006, Journal of Histochemistry and Cytochemistry, doi:10.1369/jhc.6A6999.2006

Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis
Laura E. Parton, Patrick J. McMillen, Yingnian Shen, Elizabeth Docherty, Erin Sharpe, Frédérique Diraison, Celia P. Briscoe, and Guy A. Rutter.
Am J Physiol Endocrinol Metab 291: E982-E994, June 2006; doi:10.1152/ajpendo.00067.2006 0193-1849/06

Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome
Carol A Gilchrist, Eric Houpt, Nino Trapaidze, Zhangjun Fei, Oswald Crasta, Amon Asgharpour, Clive Evans, Susan Martino-Catt, Duza J Baba, Suzanne Stroup, Shinjiro Hamano, Gretchen Ehrenkaufer, Mami Okada, Upinder Singh, Tomoyoshi Nozaki, Barbara J Mann, William A Petri Jr. June 2006, Molecular and Biochemical Parasitology, 147:163-176

Candidate Tumor-Suppressor Gene DLEC1 Is Frequently Downregulated by Promoter Hypermethylation and Histone Hypoacetylation in Human Epithelial Ovarian Cancer
Joseph Kwong, Ji-Young Lee, Kwong-Kwok Wong, Xiaofeng Zhou, David T. W. Wong, Kwok-Wai Lo, William R. Welch, Ross S. Berkowitz and Samuel C. Mok.
Neoplasia, Vol. 8, No. 4, April 2006, pp. 268-278

Lineage specification and plasticity in CD19-early B cell precursors
Lynn L. Rumfelt, Yan Zhou, Benjamin M. Rowley, Susan A. Shinton, and Richard R. Hardy.
Journal of Experimental Medicine, March 2006 Vol. 203, No. 3, March 2006 675-687

Microarray Analysis of Retinal Gene Expression in the DBA/2J Model of Glaucoma
Michael R. Steele, Denise M. Inman, David J. Calkins, Philip J. Horner, and Monica L. Vetter. March 2006, Investigative Ophthalmology and Visual Science, 47:977-985

The Aryl Hydrocarbon Receptor Agonist 2,3,7,8-Tetrachlorodibenzo-p-dioxin Alters the Circadian Rhythms, Quiescence, and Expression of Clock Genes in Murine Hematopoietic Stem and Progenitor Cells
Russell W. Garrett and Thomas A. Gasiewicz. Mol. Pharmacology, June 2006, 69 (6):2076–2083

Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling
Vigdis Nygaard and Eivind Hovig. February 2006, Nucleic Acids Research 2006 34(3):996-1014

Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors
Masayuki Akimoto, Hong Cheng, Dongxiao Zhu, Joseph A. Brzezinski, Ritu Khanna, Elena Filippova, Edwin C. T. Oh, Yuezhou Jing, Jose-Luis Linares, Matthew Brooks, Sepideh Zareparsi, Alan J. Mears, Alfred Hero, Tom Glaser, and Anand Swaroop. Published online February 2006, PNAS Vol. 103, no. 10, 3890-3895

Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell Carcinoma
Robbert J.C. Slebos, Yajun Yi, Kim Ely, Jesse Carter, Amy Evjen, Xueqiong Zhang, Yu Shyr, Barbara M. Murphy, Anthony J. Cmelak, Brian B. Burkey, James L. Netterville, Shawn Levy, Wendell G. Yarbrough and Christine H. Chung. February 2006, Clinical Cancer Research Vol. 12, 701-709

2005

A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm's canal endothelial cells Nervous System
J A Alvarado, R G Alvarado, R F Yeh, L Franse-Carman, G R Marcellino and M J Brownstein. November 2005, British Journal of Ophthalmology 2005;89:1500-1505

Central Nervous System Drug Development: An Integrative Biomarker Approach toward Individualized Medicine
B. Gomez-Mancilla, E. Marrer, J. Kehren, A. Kinnunen, G. Imbert, R. Hillebrand, M. Bergström and M. E. Schmidt. October 2005, NeuroRx: J American Society for Experimental NeuroTheraputics Vol 2: 683-695

NovaChip Evanescent Resonator Technology
Dieter Neuschäfer, Estelle Marrer and Wolfgang Budach at Novartis Pharma AG, September 2005, Innovations in Pharmaceutical Technology 78-82

Interactions Between Endothelia of the Trabecular Meshwork and of Schlemm's Canal: A New Insight into the Regulation of Aqueous Outflow in the Eye
Jorge A. Alvarado, Ru-Fang Yeh, Linda Franse-Carman, George Marcellino, and Michael J. Brownstein, 2005, Transactions of the American Ophthalmological Society Vol 103, 148-163

Novel Isothermal, Linear Nucleic Acid Amplification Systems for Highly Multiplexed Applications
Nurith Kurn, Pengchin Chen, Joe Don Heath, Anne Kopf-Sill, Kathryn M. Stephens, Shenglong Wang, September 2005, Clinical Chemistry 51: 1973-1981

Foxl2 is required for commitment to ovary differentiation
Chris Ottolenghi, Shakib Omari, J. Elias Garcia-Ortiz, Manuela Uda, Laura Crisponi, Antonino Forabosco, Giuseppe Pilia and David Schlessinger. June 2005, Human Molecular Genetics 14(14):2053-2062

Microarray-based comparison of three amplification methods for nanogram amounts of total RNA
Ruchira Singh, Rajanikanth J. Maganti, Sairam V. Jabba, Martin Wang, Glenn Deng, Joe Don Heath, Nurith Kurn, and Philine Wangemann. May 2005, Am J Physiol Cell Physiol 288: C1179-C1189

Increase DNA microarray hybridization specificity using sscDNA targets
Christopher S. Barker, Chandi Griffin, Gregory M. Dolganov, Kristina Hanspers, Jean Yee Hwa Yang, and David J. Erle. Apr 2005, BMC Genomics, 6:57

Transcriptional profiling of pig embryogenesis by using a 15K member unigene set specific for pig reproductive tissues and embryos
K.M. Whitworth, C. Agca, J.-G. Kim, R.V. Patel, G.K. Springer, N. Bivens, L.J. Forrester, N. Mathialagan, J.A. Green, R.S. Prather, Feb 2005, Biology of Reproduction; 72: 1437-1451

A mouse model for study of systemic HIV-1 infection, antiviral immune responses, and neuroinvasiveness
Mary Jane Potash, Wei Cha, Galina Bentsman, Nicolae Paris, Manisha Saini, Jadwiga Nitkiewicz, Paula Belem, Leroy Sharer, Andrew I. Brooks, and David J. Volsky. Jan 2005, PNAS 102: 3760-3765

2004

Linear mRNA amplification from as little as 5ng total RNA for global gene expression analysis
Alan Dafforn, Pengchin Chen, Glenn Deng, Michael Herrler, Dawn Iglehart, Sriveda Koritala, Susan Lato, Susheela Pillarisetty, Reshma Purohit, Martin Wang, Shenglong Wang, and Nurith Kurn. Nov 2004, BioTechniques 37:854-857

Genetic Engineering News: Sample Preparation for RNA Expression Analysis
Nurith Kurn, Ph.D. and Joe Don Heath, Feb 2004, Genetic Engineering News, Volume 24, Number 3