Publications

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2008

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe, Shintaro Sato, Kazufumi Matsushita, Hiroki Kato, Kosuke Matsui, Yutaro Kumagai, Tatsuya Saitoh, Taro Kawai, Osamu Takeuchi & Shizuo Akira
Nature Immunology, June 2008, VOLUME 9 NUMBER 6, 684-691
 

Phenotypic Analysis of Prostate-Infiltrating Lymphocytes Reveals TH17 and Treg Skewing
Karen Sandell Sfanos, Tullia C. Bruno, Charles H.Maris, Lauren Xu, Christopher J. Thoburn, Angelo M. DeMarzo, Alan K. Meeker, William B. Isaacs, and Charles G. Drake
Clinical Cancer Research, June 2008;14(11):3254-3261

Generation of a non-small cell lung cancer transcriptome microarray
Austin Tanney, Gavin R Oliver, Vadim Farztdinov, Richard D Kennedy, Jude M Mulligan, Ciaran E Fulton, Susan M Farragher, John K Field, Patrick G Johnston, D Paul Harkin, Vitali Proutski and Karl A Mulligan
BMC Medical Genomics, May 2008, 1:20 doi:10.1186/1755-8794-1-20

Affymetrix Whole-Transcript Human Gene 1.0 ST array is highly concordant with standard 3′ expression arrays  
Sylvain Pradervand, Alexandra Paillusson, Jérôme Thomas, Johann Weber, Pratyaksha Wirapati, Otto Hagenbüchle, and Keith Harshman 
BioTechniques® May 2008 Volume 44, Number 6: pp 759-762

Identification of new genes in Sinorhizobium meliloti using the Genome Sequencer FLX system
Chunhong Mao, Clive Evans, Roderick V Jensen and Bruno WS Sobral
BMC Microbiology May 2008, 8:72doi:10.1186/1471-2180-8-72

In vivo endothelial gene regulation in diabetes
J Gregory Maresh and Ralph V Shohet
BMC Cardiovascular Diabetology, April 2008, 7:8 doi:10.1186/1475-2840-7-8

Plasticity in Tumor-Promoting Inflammation: Impairment of Macrophage Recruitment Evokes a Compensatory Neutrophil Response 
Jessica C Pahler, Simon Tazzyman, Neta Erez, Yung-Yi Chen, Craig Murdoch, Hiroaki Nozawa, Claire E Lewis, and Douglas Hanahan 
2008 April, Neoplasia, 10(4): 329-339

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer
Theresa Casey, Jeffrey Bond, Scott Tighe, Timothy Hunter, Laura Lintault, Osman Patel, Jonathan Eneman, Abigail Crocker, Jeffrey White, Joseph Tessitore, Mary Stanley, Seth Harlow, Donald Weaver, Hyman Muss and Karen Plaut
Breast Cancer Research and Treatment 0167-6806, March 2008, DOI: 10.1007/s10549-008-9982-8

Expression of Stimulated by Retinoic Acid Gene 8 (Stra8) and Maturation of Murine Gonocytes and Spermatogonia Induced by Retinoic Acid In Vitro
Qing Zhou, Ying Li, Rong Nie, Patrick Friel, Debra Mitchell, Ryan M. Evanoff , Derek Pouchnik, Brent Banasik, John R. McCarrey, Christopher Small, and Michael D. Griswold
BIOLOGY OF REPRODUCTION 78, 537-545, Issue 3, March 2008, DOI: 10.1095/biolreprod.107.064337

Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques 
Stephen W. Waldo, Yifu Li, Chiara Buono, Bin Zhao, Eric M. Billings, Janet Chang and Howard S. Kruth
American Journal of Pathology. 2008;172:1112-1126. doi:10.2353/ajpath.2008.070513 on March 5, 2008

Preventing cervical ripening: the primary mechanism by which progestational agents prevent preterm birth?
Hua Xu PhD, Juan M. Gonzalez MD, Ella Oforia and Michal A. Elovitz MD
March 2008, American Journal of Obstetrics and Gynecology, 198 (3), p.314.e1-314.e8,

Integrated Genomic Profiling of Chronic Lymphocytic Leukemia Identifies Subtypes of Deletion 13q14
Peter Ouillette, Harry Erba, Lisa Kujawski, Mark Kaminski, Kerby Shedden and Sami N. Malek
Cancer Research 68, 1012-1021, February 2008. DOI: 10.1158/0008-5472.CAN-07-3105

Isolation and Molecular Characterization of Cancer Stem Cells in MMTV-Wnt-1 Murine Breast Tumors
Robert W. Cho, Xinhao Wang, Maximilian Diehn, Kerby Shedden, Grace Y. Chen, Gavin Sherlock, Austin Gurney, John Lewicki, Michael F. Clarke Stem Cells Vol. 26 No. 2 February 2008, pp. 364-371; doi:10.1634/stemcells.2007-0440

An Erythroid Differentiation Signature Predicts Response to Lenalidomide in Myelodysplastic Syndrome
Benjamin L. Ebert, Naomi Galili, Pablo Tamayo, Jocelyn Bosco, Raymond Mak, Jennifer Pretz, Shyam Tanguturi, Christine Ladd-Acosta, Richard Stone, Todd R. Golub, Azra Raza. February 2008, PLoS Medicine Vol. 5, No. 2, e35. doi:10.1371/journal.pmed.0050035

Complementary RNA Amplification Methods Enhance Microarray Identification of Transcripts Expressed in the C. elegans Nervous System
Joseph D Watson, Shenglong Wang, Stephen E Von Stetina, W Clay Spencer, Shawn Levy, Phillip J Dexheimer, Nurith Kurn, Joe Don Heath and David M Miller III. February 2008, BMC Genomics, doi:10.1186/1471-2164-9-84

Transcriptional profiling of the megabladder mouse: A unique model of bladder dysmorphogenesis
Singh S, Robinson M, Ismail I, Saha M, Auer H, Kornacker K, Robinson ML, Bates CM, McHugh KM. January 2008, Developmental Dynamics , Volume 237, issue 1, 170-186

CD4+CD25+ regulatory T cells in the small intestinal lamina propria show an effector/memory phenotype
Zijin Guo, Myoung Ho Jang, Kazuhiro Otani, Zhongbin Bai, Eiji Umemoto, Masanori Matsumoto, Mika Nishiyama, Mikako Yamasaki, Satoshi Ueha, Kouji Matsushima, Takako Hirata and Masayuki Miyasaka.  International Immunology Advance Access published online on January 9, 2008 doi:10.1093/intimm/dxm143

2007

Morphological Changes Associated with Aging: Age Spots and the Microinflammatory Model of Skin Aging
Earl Goyarts, Neelam Muizzuddin, Daniel Maes, and Paolo U. Giacomoni
Molecular Mechanisms and Models of Aging Volume 1119, Ann. N.Y. Acad. Sci. 1119: 32-39, December 2007, DOI: 10.1196/annals.1404.006

Gene Expression Profiling of Peripheral Blood From Patients With Untreated New-Onset Systemic Juvenile Idiopathic Arthritis Reveals Molecular Heterogeneity That May Predict Macrophage Activation Syndrome
Ndate Fall, Michael Barnes, Sherry Thornton, Lorie Luyrink, Judyann Olson, Norman T. Ilowite, Beth S. Gottlieb, Thomas Griffin, David D. Sherry, Susan Thompson, David N. Glass, Robert A. Colbert, and Alexei A. Grom
ARTHRITIS & RHEUMATIS, Vol. 56, No. 11, November 2007, pp 3793-3804, DOI 10.1002/art.22981

The Transcriptome and Metabolic Gene Signature of Protoplasmic Astrocytes in the Adult Murine Cortex 
Ditte Lovatt, Ursula Sonnewald, Helle S. Waagepetersen, Arne Schousboe, Wei He, Jane H.-C. Lin, Xiaoning Han, Takahiro Takano, Su Wang, Fraser J. Sim, Steven A. Goldman, and Maiken Nedergaard, The Journal of Neuroscience, November 7, 2007, 27(45):12255-12266; doi:10.1523/JNEUROSCI.3404-07.2007

Comparison of Longitudinal Leukocyte Gene Expression after Burn Injury or Trauma-Hemorrhage in Mice
James A Lederer, Bernard H. Brownstein, M. Cecilia Lopez, Sandra MacMillan, Adam J Delisle, Malcolm P MacConmara, Mashkoor A Choudhry, Wenzhong Xiao, Steven Lekousi, J. Perren Cobb, Henry V. Baker, John A Mannick, and Irshad H. Chaudry, November 2007, Physiological Genomics, doi:10.1152/00086.2007

HOXB4's road map to stem cell expansion 
Bernhard Schiedlmeier, Ana Cristina Santos, Ana Ribeiro, Natalia Moncaut, Dietrich Lesinski, Herbert Auer, Karl Kornacker, Wolfram Ostertag, Christopher Baum, Moises Mallo, and Hannes Klump, PNAS, October 23, 2007, vol. 104, no. 43, 16952-16957

Gene Expression Profiles as Markers of Aggressive Disease—EGFR as a Factor
Christine H. Chung, Joel Parker, Shawn Levy, Robbert J. Slebos, Adam P. Dicker, Ulrich Rodeck
International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 2, Supplement, October 2007, Inaugural Multidisciplinary Head and Neck Cancer Symposium

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
Prescott G. Woodruff, Homer A. Boushey, Gregory M. Dolganov, Chris S. Barker, Yee Hwa Yang, Samantha Donnelly, Almut Ellwanger, Sukhvinder S. Sidhu, Trang P. Dao-Pick, Carlos Pantoja, David J. Erle, Keith R. Yamamoto, and John V. Fahy
PNAS, October 2007, vol. 104, no. 40, 15858-15863

Gene expression analysis in pregnant women and their infants identifies unique fetal biomarkers that circulate in maternal blood
Jill L. Maron, Kirby L. Johnson, Donna Slonim, Chao-Qiang Lai, Marco Ramoni, Gil Alterovitz, Zina Jarrah, Zinger Yang, and Diana W. Bianchi , September 2007, The Journal of Clinical Investigation , Volume 117, issue 10, 3007—3019

Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells
Chris Ottolenghi, Emanuele Pelosi, Joseph Tran, Maria Colombino, Eric Douglass, Timur Nedorezov, Antonio Cao, Antonino Forabosco and David Schlessinger
Human Molecular Genetics, August 2007, Vol. 16, No. 23 2795-2804

Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats
Ana Guijarro, Susumu Suzuki, Chung Chen, Henriette Kirchner, Frank A. Middleton, Sergiy Nadtochiy, Paul S. Brookes, Akira Niijima, Akio Inui, and Michael M. Meguid
Am J Physiol Regul Integr Comp Physiol, 293 (4): R1474, July 2007

Big Results from Small Samples: Evaluation of Amplification Protocols
for Gene Expression Profiling.

Agnes Viale, Juan Li, Jay Tiesman, Susan Hester, Aldo Massimi, Chandi Griffin, George Grills, Greg Khitrov, Kathryn Lilley, Kevin Knudtson, Bill Ward, Karl Kornacker, Chin-yi Chu, Herbert Auer, and Andrew I. Brooks, July 2007, Journal of Biomolecular Techniques, Volume 18, issue 3, 150-161. Winner of the JBT "Outstanding Manuscript" Award

Identification and expression analysis of genes associated with bovine blastocyst formation
Karen Goossens, Ann Van Soom, Mario Van Poucke, Leen Vandaele,
Jo Vandesompele, Alex Van Zeveren and Luc J Peelman
June 2007, BMC Developmental Biology, 7:64 doi:10.1186/1471-213X-7-64

Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor
Saurabh Joshi, Holly Davies, Lauren Porter Sims, Shawn E Levy and Jurrien Dean. June 2007, BMC Developmental Biology, 7:67 doi:10.1186/1471-213X-7-67

IRAK-4 Kinase Activity Is Required for Interleukin-1 (IL-1) Receptor- and Toll-like Receptor 7-mediated Signaling and Gene Expression
Magdalena Koziczak-Holbro, Claire Joyce, Anton Glück, Bernd Kinzel, Matthias Müller, Claude Tschopp, John C. Mathison, Christopher N. Davis, and Hermann Gram
J. Biol. Chem., Vol. 282, Issue 18, 13552-13560, May 2007; doi:10.1074/jbc.M700548200

Zscan4: a novel gene expressed exclusively in late 2-cell embryos and embryonic stem cells 
Geppino Falco, Sung-Lim Lee, Ilaria Stanghellini, Uwem C. Bassey, Toshio Hamatani and Minoru S. H. Ko
Published online 2007 May 8. doi: 10.1016/j.ydbio.2007.05.003

Towards the uniform distribution of null P values on Affymetrix microarrays
Anthony A Fodor, Timothy L Tickle and Christine Richardson
May 2007, Genome Biology, 8:R69 (doi:10.1186/gb-2007-8-5-r69)

Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays
Herbert Auer, David L Newsom, Norma J Nowak, Kirk M McHugh, Sunita Singh, Chack-Yung Yu, Yan Yang, Gail D Wenger, Julie M Gastier- Foster and Karl Kornacker
BMC Genomics April 2007, 8:111 doi:10.1186/1471-2164-8-111

Spatial Analysis of Arabidopsis thaliana Gene Expression in Response to Turnip mosaic virus Infection
Chunling Yang, Rong Guo, Fei Jie, Dan Nettleton, Jiqing Peng, Tyrell Carr, Joanne M. Yeakley, Jian-Bing Fan, and Steven A. Whitham.
Molecular Plant-Microbe Interactions April 2007, Volume 20, Number 4, Pages 358-370 DOI: 10.1094/MPMI-20-4-0358

Comparison of Amplification Methods to Produce Affymetrix GeneChip Target Material.
Dennis Burian, Vicky White, Mark Huggins, Doris Kupfer, Dennis V. Canfield, James E. Whinnery. Civil Aerospace Medical Institute, Federal Aviation Administration
DOT/FAA/AM-07/9 report, April 2007

Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Sherwood, R.I., Jitianu, C., Cleaver, O., Shaywitz, D.A., Lamenzo, J.O., Chen, A.E., Golub, T.R., Melton, D.A. Developmental Biology, 304 (2), p.541-555, Apr 2007

Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis
Jennifer R. Wood, Daniel A. Dumesic, David H. Abbott, and Jerome F. Strauss III
The Journal of Clinical Endocrinology & Metabolism, February 2007, 92(2):705-713

Cross-Species Translocation of mRNA from Host Plants into the Parasitic Plant Dodder1[OA]
Jeannine K. Roney, Piyum A. Khatibi, and James H. Westwood. Plant Physiology, February 2007, Vol. 143, pp. 1037–1043

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
Carey N. Lumeng, Stephanie M. DeYoung, Jennifer L. Bodzin, and Alan R. Saltiel.
Diabetes 56:16-23, January 2007

Archived publications 2004-2006