NuGEN Enables Deep Multiplexing with the Encore™ 384 Multiplex System
High throughput multiplexing of NGS libraries yields reduced sequencing costs
San Carlos, CA—July 7, 2011— NuGEN Technologies, Inc., a market leader in the development of sample preparation solutions for Next Generation Sequencing (NGS) applications has revolutionized high-throughput NGS library preparation with the introduction of the Encore 384 Multiplex System. The technology utilizes a refined set of barcodes that may be used in a number of combinations to provide flexible multiplexing capability of up to 384 uniquely coded libraries. This unique solution for deep multiplexing allows scientists to undertake large scale projects while greatly reducing costs.
Accelerated sequencing throughput has created challenges in upstream sample preparation, particularly for projects involving large numbers of samples requiring relatively shallow sequencing coverage as costs associated with these projects can be prohibitive. The ability to multiplex a large number of sequencing libraries in the same sequencing run leverages platform capacities and enables higher throughput at a lower cost per sample. NuGEN's Encore 384 Multiplex System employs the same workflow as NuGEN's NGS Library Systems for single sample libraries, allowing for standardization on one method.
"NuGEN recognized that the critical need for large scale multiplexing solutions was not being met in the market", said Dr. Joe Don Heath, VP of Global Technical Services and Automation at NuGEN Technologies. "We continue innovation of leading edge solutions for our customers to accelerate their research and enable discovery. Our focus on providing streamlined, automatable, and cost effective workflows, such as the Encore 384 Multiplex System, will continue to aid these efforts."
The Encore 384 Multiplex system is compatible with high-throughput automation and has been fully automated on the Sciclone® NGS Workstation by Caliper Life Sciences as part of an on-going collaboration between NuGEN and Caliper to provide automation of sample processing for a wide range of samples and applications. "Caliper's Sciclone NGS Workstation significantly accelerates high throughput library preparation" said Dr. Nate Cosper, Division VP, Commercial Operations at Caliper Life Sciences. "Caliper and NuGEN are working collaboratively with leading scientists to provide scalable solutions for high quality library construction that meet the demands for cost and efficiency."
NuGEN Technologies is a San Carlos, CA company focused on innovative sample preparation solutions for RNA and DNA that enable life scientists to do more with less. With reagent solutions that are quick, easy to use, and amenable to automation, NuGEN empowers researchers to prepare genomic samples of any size, from almost any source, regardless of the intended application or technology platform. For more information please visit www.nugeninc.com.
Encore is a trademark and NuGEN is a registered trademark of NuGEN Technologies, Inc.
About Caliper Life Sciences
Caliper Life Sciences is a premier provider of cutting-edge technologies enabling researchers in the life sciences industry to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper is aggressively innovating new technology to bridge the gap between in vitro assays and in vivo results, enabling the translation of those results into cures for human disease. Caliper's portfolio of offerings includes state-of- the-art microfluidics, lab automation and liquid handling, optical imaging technologies, and discovery and development outsourcing solutions. For more information please visit www.caliperLS.com.
Caliper, and Sciclone are registered trademarks of Caliper Life Sciences, Inc.